Dressing for Odd Body type and Losing my spare tire?

Ok so I am about 24 yrs old have the odds body shaped ever!! I and very large breasted with a small waist hidden under neath this god awful spare tire! I have actually weighed the most I have ever weighed in my entire life right now I am weighing at a whopping 180 lbs. and I an about 5"2" or 5"3"! I am having the hardest time finding clothes and on top of all the I wear girdles all the time I wear like 3 and 4 at a time!! I hear it's not good but I don't like the way my body pushes down my clothes and if I buy a size bigger the clothes fall off with or with out the girdles!! I want to know how to lose the weight the most effective way as well as how do I dress for this kind of body! I actually was always I smaller girl until one day I just blew up I went from being my Ritalin and 3 other medications my step mother had me on as well as the depo shot to coming off all of all at once I gained nothing but weight!! I am also concerned about the whole gaining the way i did after the medications. I know my meds were depo shot(birth control), ritalin, zyprexa, depakote, and one other i can't seem to remember!! all I know I was on these meds as young child and they took a major tole in me and my body! Ritalin is something I have always been on since I was in second grade so I know that didn't have a effect but I think the mixing of them all has a part in all this!!